Acute necrotizing encephalopathy in an adult as a complication of H1N1 infection

Fatal H1N1-Related Acute Necrotizing Encephalopathy in an Adult

Acute necrotizing encephalopathy (ANE) is a severe neurological complication of influenza infection, including H1N1 influenza. Many cases of ANE have been reported in the pediatric literature, but very few cases have been described in adults. The cause of ANE remains unknown-the influenza virus is not known to be neurotropic, and evidence of direct viral involvement of the central nervous syste...

retroperitoneal necrotizing soft tissue infection in a healthy adult masquerading as acute pancreatitis

necrotizing soft tissue infections (nstis) are polymicrobial infections with high morbidity and mortality. we report a case of retroperitoneal nsti in an immunocompetent young male, with clinical symptoms and signs mimicking acute pancreatitis (pseudo-cullen’s and pseudo-grey-turner’s signs). the initiating lesion was a pustule which progressed and mimicked acute pancreatitis. ct scan showed fe...

Acute Necrotizing Encephalopathy: An Underrecognized Clinicoradiologic Disorder

Acute necrotizing encephalopathy (ANE) is a rare but distinctive type of acute encephalopathy with global distribution. Occurrence of ANE is usually preceded by a virus-associated febrile illness and ensued by rapid deterioration. However, the causal relationship between viral infections and ANE and the exact pathogenesis of ANE remain unclear; both environmental and host factors might be invol...

Acute necrotizing encephalopathy progressing to brain death in a pediatric patient with novel influenza A (H1N1) infection.

We report a case of encephalopathy progressing to brain death in a pediatric patient with confirmed infection with novel influenza H1N1. Although neurologic dysfunction associated with H1N1 has been described, we believe this to be the first published report of brain death associated with H1N1 infection.

Cutaneous scrotal fistula as a complication of acute necrotizing pancreatitis